Acetyl-CoA Carboxylase alpha 抗体 (AA 2223-2346)
Quick Overview for Acetyl-CoA Carboxylase alpha 抗体 (AA 2223-2346) (ABIN5701229)
抗原
See all Acetyl-CoA Carboxylase alpha (ACACA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2223-2346
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原理
- ACACA antibody
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免疫原
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Immunogen sequence: 2223-2346aa
Immunogen: acetyl-Coenzyme A carboxylase alpha
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亚型
- IgG
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应用备注
- WB :1:200-1:2000,IHC:1:20-1:200,IF:1:20-1:200,IP:1:200-1:2000
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说明
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab00077(ACACA antibody) at dilution of 1:500
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months
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有效期
- 12 months
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- Acetyl-CoA Carboxylase alpha (ACACA)
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别名
- ACACA
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背景
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Synonyms: Acetyl-CoA carboxylase 1 (ACC1)|Acetyl-Coenzyme A carboxylase alpha (ACC-alpha)|ACACA|ACAC|ACC1|ACCA
Background: ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.
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分子量
- 270kDa
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UniProt
- Q13085
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途径
- AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect
抗原
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